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Merck

TNFRSF13C

tumor necrosis factor receptor superfamily, member 13C

Sinónimos:
BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin
Especie:
ID UniProtKB:
ID del gen:
  • Human(115650) Summary: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
  • Mouse(72049) tumor necrosis factor receptor superfamily, member 13c
  • Rat(500910) tumor necrosis factor receptor superfamily, member 13c
  • chicken(417983) tumor necrosis factor receptor superfamily, member 13C
  • dog(607785) tumor necrosis factor receptor superfamily, member 13C
  • Horse(100070724) tumor necrosis factor receptor superfamily, member 13C
  • domestic guinea pig(100713376) tumor necrosis factor receptor superfamily, member 13C
  • naked mole-rat(101700523) tumor necrosis factor receptor superfamily, member 13C
  • domestic cat(101090370) tumor necrosis factor receptor superfamily, member 13C
  • sheep(101104901) tumor necrosis factor receptor superfamily, member 13C

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-BAFF receptor Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Tnfrsf13c,
Especie
mouse