TLR4
toll-like receptor 4
Sinónimos:
ARMD10, CD284, TLR-4, TOLL
Especie:
Human TLR4 (7099), Mouse Tlr4 (21898), Rat Tlr4 (29260), naked mole-rat Tlr4 (101715916), dog TLR4 (403417), cow TLR4 (281536), Horse TLR4 (100066890), Domestic Rabbit TLR4 (100009497), sheep TLR4 (554263), Goat TLR4 (100860955) ...Más
ID UniProtKB:
ID del gen:
- Human(7099) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
- Mouse(21898) toll-like receptor 4
- Rat(29260) toll-like receptor 4
- naked mole-rat(101715916) toll-like receptor 4
- dog(403417) toll-like receptor 4
- cow(281536) toll-like receptor 4
- Horse(100066890) toll-like receptor 4
- Domestic Rabbit(100009497) toll-like receptor 4
- sheep(554263) toll-like receptor 4
- Goat(100860955) toll-like receptor 4
- domestic guinea pig(100724803) toll-like receptor 4
- domestic cat(493698) toll-like receptor 4
- chicken(417241) toll-like receptor 4
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TLR4 Antibody, clone 2N20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
flow cytometry
immunocytochemistry
immunohistochemistry
Anti-TLR4 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, rat
Aplicación
western blot
Anti-TLR4 Mouse mAb (1H7), liquid, clone 1H7, Calbiochem®,
Reactividad de especies
human
Aplicación
esiRNA
Referencia del producto
Descripción
Especie