TDO2
tryptophan 2,3-dioxygenase
Sinónimos:
TDO, TO, TPH2, TRPO
Especie:
Human TDO2 (6999), Mouse Tdo2 (56720), Rat Tdo2 (64206), dog TDO2 (475476), chicken TDO2 (422409), sheep TDO2 (101109739), Domestic Rabbit TDO2 (100344083), cow TDO2 (530397), Horse TDO2 (100069524), domestic cat TDO2 (101090935) ...Más
ID UniProtKB:
ID del gen:
- Human(6999) Summary: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
- Mouse(56720) tryptophan 2,3-dioxygenase
- Rat(64206) tryptophan 2,3-dioxygenase
- dog(475476) tryptophan 2,3-dioxygenase
- chicken(422409) tryptophan 2,3-dioxygenase
- sheep(101109739) tryptophan 2,3-dioxygenase
- Domestic Rabbit(100344083) tryptophan 2,3-dioxygenase
- cow(530397) tryptophan 2,3-dioxygenase
- Horse(100069524) tryptophan 2,3-dioxygenase
- domestic cat(101090935) tryptophan 2,3-dioxygenase
- naked mole-rat(101711781) tryptophan 2,3-dioxygenase
- domestic guinea pig(100727713) tryptophan 2,3-dioxygenase
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Antibodies
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Anti-TDO2 Antibody, clone 7A6.1, clone 7A6.1, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Small Molecule - Precursor
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Proteins
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esiRNA
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