Saltar al contenido
Merck

TAPBP

TAP binding protein (tapasin)

Sinónimos:
NGS17, TAPA, TPN, TPSN
Especie:
ID UniProtKB:
ID del gen:
  • Human(6892) Summary: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(21356) TAP binding protein
  • Rat(25217) TAP binding protein (tapasin)
  • dog(481740) TAP binding protein (tapasin)
  • naked mole-rat(101719224) TAP binding protein (tapasin)
  • chicken(417048) TAP binding protein (tapasin)
  • Zebrafish(30163) TAP binding protein
  • domestic cat(101091023) TAP binding protein (tapasin)
  • sheep(100170652) TAP binding protein (tapasin)
  • domestic guinea pig(100735947) TAP binding protein (tapasin)
  • Horse(100061515) TAP binding protein (tapasin)
  • cow(504335) TAP binding protein (tapasin)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Tapasin Antibody, clone 7F6, clone 7F6, from rat,
Reactividad de especies
human
Aplicación
flow cytometry
Anti-Tapasin, from rabbit,
Reactividad de especies
mouse
Aplicación
immunoprecipitation (IP)
western blot
Anti-TAPBP antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, horse, human, mouse, pig, rat, sheep
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TAPBP (2),
Especie
human
MISSION® esiRNA, targeting human TAPBP (1),
Especie
human