SVIL
supervillin
Sinónimos:
Especie:
Human SVIL (6840), Mouse Svil (225115), Rat Svil (361256), cow SVIL (281509), dog SVIL (477965), domestic cat SVIL (101098723), domestic guinea pig Svil (100729448), Horse SVIL (100063045), naked mole-rat Svil (101713658), chicken SVIL (420475)
ID UniProtKB:
ID del gen:
- Human(6840) Summary: This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Two transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Jul 2008]
- Mouse(225115) supervillin
- Rat(361256) supervillin
- cow(281509) supervillin
- dog(477965) supervillin
- domestic cat(101098723) supervillin
- domestic guinea pig(100729448) supervillin
- Horse(100063045) supervillin
- naked mole-rat(101713658) supervillin
- chicken(420475) supervillin
- sheep(101119493) supervillin
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.