STAT4
signal transducer and activator of transcription 4
Sinónimos:
SLEB11
Especie:
Human STAT4 (6775), Mouse Stat4 (20849), Rat Stat4 (367264), sheep STAT4 (101117562), dog STAT4 (478845), domestic guinea pig Stat4 (100726892), Domestic Rabbit STAT4 (100344146), domestic cat STAT4 (101080650), naked mole-rat Stat4 (101718558), Zebrafish stat4 (368519) ...Más
ID UniProtKB:
ID del gen:
- Human(6775) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
- Mouse(20849) signal transducer and activator of transcription 4
- Rat(367264) signal transducer and activator of transcription 4
- sheep(101117562) signal transducer and activator of transcription 4
- dog(478845) signal transducer and activator of transcription 4
- domestic guinea pig(100726892) signal transducer and activator of transcription 4
- Domestic Rabbit(100344146) signal transducer and activator of transcription 4
- domestic cat(101080650) signal transducer and activator of transcription 4
- naked mole-rat(101718558) signal transducer and activator of transcription 4
- Zebrafish(368519) signal transducer and activator of transcription 4
- cow(515988) signal transducer and activator of transcription 4
- chicken(768406) signal transducer and activator of transcription 4
- Horse(100054693) signal transducer and activator of transcription 4
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Antibodies
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Descripción
Reactividad de especies
Aplicación
Anti-Phospho-STAT4-Y693 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-STAT4 Antibody, clone 10H10O9, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
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Descripción
Especie