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Merck

STARD4

StAR-related lipid transfer (START) domain containing 4

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(134429) Summary: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]
  • Mouse(170459) StAR-related lipid transfer (START) domain containing 4
  • Rat(291699) StAR-related lipid transfer (START) domain containing 4
  • chicken(769322) StAR-related lipid transfer (START) domain containing 4
  • domestic cat(101086371) StAR-related lipid transfer (START) domain containing 4
  • dog(479141) StAR-related lipid transfer (START) domain containing 4
  • cow(100847750) StAR-related lipid transfer (START) domain containing 4
  • sheep(101108571) StAR-related lipid transfer (START) domain containing 4
  • domestic guinea pig(100724156) StAR-related lipid transfer (START) domain containing 4
  • naked mole-rat(101700970) StAR-related lipid transfer (START) domain containing 4

Custom & Knockdown Gene Products

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human STARD4,
Especie
human
MISSION® esiRNA, targeting mouse Stard4,
Especie
mouse