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Merck

SRSF2

serine/arginine-rich splicing factor 2

Sinónimos:
PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b
Especie:
ID UniProtKB:
ID del gen:
  • Human(6427) Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010]
  • Mouse(20382) serine/arginine-rich splicing factor 2
  • Rat(494445) serine/arginine-rich splicing factor 2
  • cow(508312) serine/arginine-rich splicing factor 2
  • chicken(396195) serine/arginine-rich splicing factor 2
  • naked mole-rat(101721554) serine/arginine-rich splicing factor 2
  • dog(612817) serine/arginine-rich splicing factor 2

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-SC-35 Antibody, clone 1SC-4F11, ascites fluid, clone 1SC-4F11, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
western blot
Anti-SFRS2 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, guinea pig, human, mouse, rat, zebrafish
Aplicación
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human SRSF2,
Especie
human