SNX15
sorting nexin 15
Sinónimos:
HSAF001435
Especie:
Human SNX15 (29907), Mouse Snx15 (69024), Rat Snx15 (293691), Zebrafish snx15 (393352), cow SNX15 (507751), dog SNX15 (612080), domestic cat SNX15 (101082093), naked mole-rat Snx15 (101702424), domestic guinea pig Snx15 (100724367), sheep SNX15 (101119948)
ID UniProtKB:
ID del gen:
- Human(29907) Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010]
- Mouse(69024) sorting nexin 15
- Rat(293691) sorting nexin 15
- Zebrafish(393352) sorting nexin 15
- cow(507751) sorting nexin 15
- dog(612080) sorting nexin 15
- domestic cat(101082093) sorting nexin 15
- naked mole-rat(101702424) sorting nexin 15
- domestic guinea pig(100724367) sorting nexin 15
- sheep(101119948) sorting nexin 15
- Goat(100861118) sorting nexin 15
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
esiRNA
Referencia del producto
Descripción
Especie