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Merck

SERPINC1

serpin peptidase inhibitor, clade C (antithrombin), member 1

Sinónimos:
AT3, AT3D, ATIII, THPH7
Especie:
ID UniProtKB:
ID del gen:
  • Human(462) Summary: The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq, Jul 2009]
  • Mouse(11905) serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
  • Rat(304917) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • chicken(424440) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • Zebrafish(321545) serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
  • Horse(100061173) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • domestic cat(101093983) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • dog(480066) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • sheep(443407) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • cow(540261) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • Domestic Rabbit(100355802) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • naked mole-rat(101722222) serpin peptidase inhibitor, clade C (antithrombin), member 1
  • domestic guinea pig(100379601) serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-SERPINC1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Serpinc1,
Especie
mouse
MISSION® esiRNA, targeting human SERPINC1,
Especie
human