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Merck

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

Sinónimos:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Especie:
ID UniProtKB:
ID del gen:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Sodium Channel Nav1.5 Antibody, pain, Chemicon®, from rabbit,
Reactividad de especies
rat
Aplicación
western blot
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, guinea pig, horse, human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-SCN5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

Small Molecule - Blocker

Número de producto
Descripción
Especie
Flecainide acetate salt, ,
Especie
human
Flecainide acetate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Flecainide acetate, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Flecainide for system suitability, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Dibucaine hydrochloride, analytical standard, ≥99%,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human SCN5A,
Especie
human