SCN2A
sodium channel, voltage-gated, type II, alpha subunit
Sinónimos:
BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2
Especie:
Human SCN2A (6326), domestic cat SCN2A (101080472), dog SCN2A (478773), chicken SCN2A (395945), naked mole-rat Scn2a (101715020), Horse SCN2A (100051816), domestic guinea pig Scn2a (100716680), sheep SCN2A (101103126), cow SCN2A (539718)
ID UniProtKB:
ID del gen:
- Human(6326) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
- domestic cat(101080472) sodium channel, voltage-gated, type II, alpha subunit
- dog(478773) sodium channel, voltage-gated, type II, alpha subunit
- chicken(395945) sodium channel, voltage-gated, type II, alpha subunit
- naked mole-rat(101715020) sodium channel, voltage-gated, type II, alpha subunit
- Horse(100051816) sodium channel, voltage-gated, type II, alpha subunit
- domestic guinea pig(100716680) sodium channel, voltage-gated, type II, alpha subunit
- sheep(101103126) sodium channel, voltage-gated, type II, alpha subunit
- cow(539718) sodium channel, voltage-gated, type II, alpha subunit
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Small Molecule - Antagonist
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Antibodies
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Anti-SCN2A Antibody, clone 5H10.2, clone 5H10.2, from mouse,
Reactividad de especies
human
Aplicación
western blot
Anti-Sodium Channel Antibody, Voltage Gated, Brain Type II, Chemicon®, from rabbit,
Reactividad de especies
mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
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Lidocaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
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human
esiRNA
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