SAFB
scaffold attachment factor B
Sinónimos:
HAP, HET, SAF-B1, SAFB1
Especie:
Human SAFB (6294), Mouse Safb (224903), Rat Safb (64196), chicken SAFB (426047), Zebrafish safb (321979), domestic guinea pig Safb (100718986), naked mole-rat Safb (101713322), domestic cat SAFB (101092244), cow SAFB (539785), dog SAFB (485028)
ID UniProtKB:
ID del gen:
- Human(6294) Summary: This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
- Mouse(224903) scaffold attachment factor B
- Rat(64196) scaffold attachment factor B
- chicken(426047) scaffold attachment factor B
- Zebrafish(321979) scaffold attachment factor B
- domestic guinea pig(100718986) scaffold attachment factor B
- naked mole-rat(101713322) scaffold attachment factor B
- domestic cat(101092244) scaffold attachment factor B
- cow(539785) scaffold attachment factor B
- dog(485028) scaffold attachment factor B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-HET/SAF-B Antibody, clone 6F7, clone 6F7, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-SAFB Antibody, clone 2N15-L2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot