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RPS6

ribosomal protein S6

Sinónimos:
S6
Especie:
ID UniProtKB:
ID del gen:
  • Human(6194) Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
  • Mouse(20104) ribosomal protein S6
  • Rat(29304) ribosomal protein S6
  • dog(474722) ribosomal protein S6
  • Thale Cress(829298) 40S ribosomal protein S6-1
  • cow(787914) ribosomal protein S6
  • Thale Cress(834690) TIR-NBS-LRR class disease resistance protein
  • fruit fly(31700) Ribosomal protein S6
  • domestic cat(101098495) ribosomal protein S6
  • domestic guinea pig(100729373) ribosomal protein S6
  • Zebrafish(445028) ribosomal protein S6
  • naked mole-rat(101723295) ribosomal protein S6
  • chicken(396148) ribosomal protein S6

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-phospho-Ribosomal Protein S6 Antibody (Ser240/Ser244), from rabbit, purified by affinity chromatography,
Reactividad de especies
xenopus, bovine, human, mouse, rat, zebrafish
Aplicación
immunocytochemistry
western blot
Anti-p-RPS6 (Ser240/244) Antibody, clone 2H10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, human, monkey, mouse, porcine
Aplicación
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-p-RPS6-Ser235/236 Antibody, clone 1I22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, human, monkey, mouse, rat, sheep
Aplicación
affinity binding assay
inhibition assay

western blot
Anti-phospho-Ribosomal Protein S6 (Ser235) Antibody, clone MC27, rabbit monoclonal, culture supernatant, clone MC27, Upstate®,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-S6 Ribosomal Protein (RPS6) Antibody, clone 4C7P4, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Rps6,
Especie
mouse
MISSION® esiRNA, targeting human RPS6,
Especie
human