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Merck

RPS3

ribosomal protein S3

Sinónimos:
S3
Especie:
ID UniProtKB:
ID del gen:
  • Human(6188) Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(27050) ribosomal protein S3
  • Rat(140654) ribosomal protein S3
  • domestic guinea pig(100725706) ribosomal protein S3
  • cow(326588) ribosomal protein S3
  • Thale Cress(814570) ribosomal protein S3
  • sheep(101108684) ribosomal protein S3
  • naked mole-rat(101702848) ribosomal protein S3
  • Zebrafish(336550) ribosomal protein S3
  • domestic cat(101092047) ribosomal protein S3
  • chicken(419069) ribosomal protein S3
  • dog(476804) ribosomal protein S3
  • fruit fly(42761) Ribosomal protein S3
  • Thale Cress(844719) 30S ribosomal protein S3

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-RPS3 Antibody, clone 3I17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, nonhuman primates, rat
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-RPS3 Antibody, clone 3X2M4, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot
Anti-RPS3 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human RPS3,
Especie
human
MISSION® esiRNA, targeting mouse Rps3,
Especie
mouse