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Merck

RNF20

ring finger protein 20, E3 ubiquitin protein ligase

Sinónimos:
BRE1, BRE1A, hBRE1
Especie:
ID UniProtKB:
ID del gen:
  • Human(56254) Summary: The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
  • Mouse(109331) ring finger protein 20
  • Rat(313216) ring finger protein 20, E3 ubiquitin protein ligase
  • Zebrafish(402838) ring finger protein 20, E3 ubiquitin protein ligase
  • domestic cat(101097522) ring finger protein 20, E3 ubiquitin protein ligase
  • cow(513326) ring finger protein 20
  • dog(474788) ring finger protein 20, E3 ubiquitin protein ligase
  • chicken(427310) ring finger protein 20, E3 ubiquitin protein ligase
  • naked mole-rat(101711656) ring finger protein 20, E3 ubiquitin protein ligase
  • domestic guinea pig(100717191) ring finger protein 20, E3 ubiquitin protein ligase
  • Domestic Rabbit(100340973) ring finger protein 20, E3 ubiquitin protein ligase
  • Horse(100054384) ring finger protein 20, E3 ubiquitin protein ligase
  • sheep(101121065) ring finger protein 20, E3 ubiquitin protein ligase

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Rnf20 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-RNF20 Antibody, clone 8N4O8, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
western blot
Anti-BRE1-A (RNF20) Antibody, clone 8A4.2, clone 8A4.2, from mouse,
Reactividad de especies
human
Aplicación
western blot
Anti-hRNF20 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human RNF20,
Especie
human