Saltar al contenido
Merck

RAPGEF1

Rap guanine nucleotide exchange factor (GEF) 1

Sinónimos:
C3G, GRF2
Especie:
Human RAPGEF1 (2889), Mouse Rapgef1 (107746), Rat Rapgef1 (63881), naked mole-rat Rapgef1 (101714387), sheep RAPGEF1 (101121164), chicken RAPGEF1 (417173), domestic cat RAPGEF1 (101099507), Horse RAPGEF1 (100069527), cow RAPGEF1 (520454), domestic guinea pig Rapgef1 (100727953)
ID UniProtKB:
Q13905, Q5JUE4, Q8IV73
ID del gen:
  • Human(2889) Summary: This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(107746) Rap guanine nucleotide exchange factor (GEF) 1
  • Rat(63881) Rap guanine nucleotide exchange factor (GEF) 1
  • naked mole-rat(101714387) Rap guanine nucleotide exchange factor (GEF) 1
  • sheep(101121164) Rap guanine nucleotide exchange factor (GEF) 1
  • chicken(417173) Rap guanine nucleotide exchange factor (GEF) 1
  • domestic cat(101099507) Rap guanine nucleotide exchange factor (GEF) 1
  • Horse(100069527) Rap guanine nucleotide exchange factor (GEF) 1
  • cow(520454) Rap guanine nucleotide exchange factor (GEF) 1
  • domestic guinea pig(100727953) Rap guanine nucleotide exchange factor (GEF) 1
  • dog(491286) Rap guanine nucleotide exchange factor (GEF) 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
MABN2643
Anti-RAPGEF1 (C3G) Antibody, clone 3F6, ,
Reactividad de especies
human, monkey, mouse, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot

esiRNA

Referencia del producto
Descripción
Especie
EHU123241
MISSION® esiRNA, targeting human RAPGEF1,
Especie
human
EMU062111
MISSION® esiRNA, targeting mouse Rapgef1,
Especie
mouse