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Merck

PSMB10

proteasome (prosome, macropain) subunit, beta type, 10

Sinónimos:
LMP10, MECL1, beta2i
Especie:
ID UniProtKB:
ID del gen:
  • Human(5699) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]
  • Mouse(19171) proteasome (prosome, macropain) subunit, beta type 10
  • Rat(291983) proteasome (prosome, macropain) subunit, beta type 10
  • domestic cat(101082199) proteasome (prosome, macropain) subunit, beta type, 10
  • naked mole-rat(101701334) proteasome (prosome, macropain) subunit, beta type, 10
  • dog(489749) proteasome (prosome, macropain) subunit, beta type, 10
  • domestic guinea pig(100730197) proteasome (prosome, macropain) subunit, beta type, 10
  • Zebrafish(64280) proteasome (prosome, macropain) subunit, beta type, 10
  • sheep(101116929) proteasome (prosome, macropain) subunit, beta type, 10
  • cow(282328) proteasome (prosome, macropain) subunit, beta type, 10

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti PSMB10 Antibody, clone 23GB2170, Rabbit Monoclonal, clone 23GB2170, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
immunofluorescence

western blot
KD-Validated Anti PSMB10 Antibody, clone 23GB2165, Rabbit Monoclonal, clone 23GB2165, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Psmb10,
Especie
mouse