PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
Sinónimos:
PKACA
Especie:
Human PRKACA (5566), Mouse Prkaca (18747), Rat Prkaca (25636), naked mole-rat Prkaca (101707235), sheep PRKACA (443094), domestic guinea pig Prkaca (100735694), dog PRKACA (403556), Horse PRKACA (100064302), cow PRKACA (282322), domestic cat PRKACA (101090494)
ID UniProtKB:
ID del gen:
- Human(5566) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(18747) protein kinase, cAMP dependent, catalytic, alpha
- Rat(25636) protein kinase, cAMP-dependent, catalytic, alpha
- naked mole-rat(101707235) protein kinase, cAMP-dependent, catalytic, alpha
- sheep(443094) protein kinase, cAMP-dependent, catalytic, alpha
- domestic guinea pig(100735694) protein kinase, cAMP-dependent, catalytic, alpha
- dog(403556) protein kinase, cAMP-dependent, catalytic, alpha
- Horse(100064302) protein kinase, cAMP-dependent, catalytic, alpha
- cow(282322) protein kinase, cAMP-dependent, catalytic, alpha
- domestic cat(101090494) protein kinase, cAMP-dependent, catalytic, alpha
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-PKA C-α Antibody, clone 2E17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-PRKACA (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Aplicación
immunohistochemistry
western blot
western blot
Anti-phospho-PKA C (Thr197) Antibody, clone 24GB1650, Rabbit Monoclonal, clone 24GB1650, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
western blot
western blot
Small Molecule - Inhibitor
Número de producto
Descripción
Especie
Protein Kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt, ≥90% (HPLC), lyophilized powder,
Especie
mouse, rat, human
Proteins
Número de producto
Descripción
Especie
PKA Protein, Recombinant, 10 µg, Recombinant human full length PKA, catalytic subunit type alpha, untagged, for use in Kinase Assays.,
Especie
Protein Kinase A catalytic subunit human, >90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Especie
human