PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
Sinónimos:
AMPK, AMPK2, AMPKa2, PRKAA
Especie:
Human PRKAA2 (5563), Mouse Prkaa2 (108079), Rat Prkaa2 (78975), sheep PRKAA2 (100127210), domestic guinea pig Prkaa2 (100713170), naked mole-rat Prkaa2 (101698482), domestic cat PRKAA2 (101096000), dog PRKAA2 (489571), cow PRKAA2 (538954), Horse PRKAA2 (100034159) ...Más
ID UniProtKB:
ID del gen:
- Human(5563) Summary: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
- Mouse(108079) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Rat(78975) protein kinase, AMP-activated, alpha 2 catalytic subunit
- sheep(100127210) protein kinase, AMP-activated, alpha 2 catalytic subunit
- domestic guinea pig(100713170) protein kinase, AMP-activated, alpha 2 catalytic subunit
- naked mole-rat(101698482) protein kinase, AMP-activated, alpha 2 catalytic subunit
- domestic cat(101096000) protein kinase, AMP-activated, alpha 2 catalytic subunit
- dog(489571) protein kinase, AMP-activated, alpha 2 catalytic subunit
- cow(538954) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Horse(100034159) protein kinase, AMP-activated, alpha 2 catalytic subunit
- chicken(429110) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Zebrafish(572074) protein kinase, AMP-activated, alpha 2 catalytic subunit
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-AMPK alpha 1/2 Antibody, clone 34.2, clone 34.2, from mouse,
Reactividad de especies
drosophila, human, mouse, rat
Aplicación
western blot
Anti- AMPKα2 antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-phospho-AMPK alpha 2 (Ser345) Antibody, clone 23GB4095, Rabbit Monoclonal, clone 23GB4095, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho-AMPK alpha 2 (Ser491) Antibody, clone 23GB5675, Rabbit Monoclonal, clone 23GB5675, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Phospho-AMPKa1/AMPKa2-T183/T172 antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
western blot
Proteins
Número de producto
Descripción
Especie
AMPK (α2, β1, γ1) Protein, active, 10 µg, Active, recombinant, human AMPK (α2, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα2, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.,
Especie
human
esiRNA
Número de producto
Descripción
Especie