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Merck

PPP1CA

protein phosphatase 1, catalytic subunit, alpha isozyme

Sinónimos:
PP-1A, PP1A, PP1alpha, PPP1A
Especie:
ID UniProtKB:
ID del gen:
  • Human(5499) Summary: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19045) protein phosphatase 1, catalytic subunit, alpha isoform
  • Rat(24668) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic guinea pig(100721697) protein phosphatase 1, catalytic subunit, alpha isozyme
  • sheep(101119264) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Horse(100059233) protein phosphatase 1, catalytic subunit, alpha isozyme
  • dog(403609) protein phosphatase 1, catalytic subunit, alpha isozyme
  • naked mole-rat(101705408) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic cat(101080405) protein phosphatase 1, catalytic subunit, alpha isozyme
  • cow(516175) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Domestic Rabbit(100009298) protein phosphatase 1, catalytic subunit, alpha isozyme

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ZAP-70 Antibody, clone 1E7.2, clone 1E7.2, Upstate®, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-PPP1CA Antibody, clone 5E9, ascites fluid, clone 5E9, from mouse,
Reactividad de especies
human
Aplicación
western blot

Proteins

Referencia del producto
Descripción
Especie
PP1α Protein, 10 µg, Recombinant, full length, human PP1α, for use in Phosphatase Assays.,
Especie
human
Protein Phosphatase-1 Catalytic Subunit, α-Isoform from rabbit, 5,000-15,000 units/mg protein, recombinant, expressed in E. coli, lyophilized powder,
Especie
domestic rabbit

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PPP1CA,
Especie
human
MISSION® esiRNA, targeting mouse Ppp1ca,
Especie
mouse