PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
PP-1A, PP1A, PP1alpha, PPP1A
Human PPP1CA (5499), Mouse Ppp1ca (19045), Rat Ppp1ca (24668), domestic guinea pig Ppp1ca (100721697), sheep PPP1CA (101119264), Horse PPP1CA (100059233), dog PPP1CA (403609), naked mole-rat Ppp1ca (101705408), domestic cat PPP1CA (101080405), cow PPP1CA (516175)
- Human(5499) Summary: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19045) protein phosphatase 1, catalytic subunit, alpha isoform
- Rat(24668) protein phosphatase 1, catalytic subunit, alpha isozyme
- domestic guinea pig(100721697) protein phosphatase 1, catalytic subunit, alpha isozyme
- sheep(101119264) protein phosphatase 1, catalytic subunit, alpha isozyme
- Horse(100059233) protein phosphatase 1, catalytic subunit, alpha isozyme
- dog(403609) protein phosphatase 1, catalytic subunit, alpha isozyme
- naked mole-rat(101705408) protein phosphatase 1, catalytic subunit, alpha isozyme
- domestic cat(101080405) protein phosphatase 1, catalytic subunit, alpha isozyme
- cow(516175) protein phosphatase 1, catalytic subunit, alpha isozyme
- Domestic Rabbit(100009298) protein phosphatase 1, catalytic subunit, alpha isozyme
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