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Merck

PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Sinónimos:
AGM7, GRB1, p85, p85-ALPHA
Especie:
Human PIK3R1 (5295), Mouse Pik3r1 (18708), Rat Pik3r1 (25513), domestic guinea pig Pik3r1 (100730242), domestic cat PIK3R1 (100271864), cow PIK3R1 (282307), sheep PIK3R1 (101121455), chicken PIK3R1 (427171), Zebrafish pik3r1 (557176), dog PIK3R1 (487235)
ID UniProtKB:
P27986, B3KT19, D3DWA0, E7EX19, Q15747, Q4VBZ7, Q53EM6, Q8IXA2
ID del gen:
  • Human(5295) Summary: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
  • Mouse(18708) phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
  • Rat(25513) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • domestic guinea pig(100730242) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • domestic cat(100271864) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • cow(282307) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • sheep(101121455) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • chicken(427171) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • Zebrafish(557176) phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
  • dog(487235) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
05-212
Anti-PI3 Kinase Antibody, p85, N-SH3, clone AB6, clone AB6, Upstate®, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot
MABS831
Anti-PI3 Kinase Antibody, p85 Antibody, N-SH3 Antibody, clone 1D5.1, clone 1D5.1, from mouse,
Reactividad de especies
human, mouse
Aplicación
western blot
ZRB1898
Anti-PI3-Kinase p85α Antibody, clone 3D12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, mouse, porcine, rat
Aplicación
affinity binding assay
immunohistochemistry
western blot
SAB5702438
Anti-PI3 Kinase p85 alpha Antibody, clone 7Z9H0, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot
ABS234
Anti-PI3 Kinase Antibody, p85, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, human, monkey, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
W1628
Wortmannin, from Penicillium funiculosum, ≥98% (HPLC and TLC),
Especie
human
W3144
Wortmannin, Ready Made Solution, from Penicillium funiculosum, ≥95% (HPLC),
Especie
human
D2926
Diphenyleneiodonium chloride, ≥98%,
Especie
mouse, human
PZ0235
PF-04691502, ≥98% (HPLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU187151
MISSION® esiRNA, targeting mouse Pik3r1,
Especie
mouse
EHU151811
MISSION® esiRNA, targeting human PIK3R1,
Especie
human