PHGDH
phosphoglycerate dehydrogenase
3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA
Human PHGDH (26227), Mouse Phgdh (236539), Rat Phgdh (58835), cow PHGDH (505103), domestic guinea pig Phgdh (100726801), sheep PHGDH (101111328), naked mole-rat Phgdh (101712402), chicken PHGDH (424381), Zebrafish phgdh (321928), domestic cat PHGDH (101088505)
- Human(26227) Summary: This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]
- Mouse(236539) 3-phosphoglycerate dehydrogenase
- Rat(58835) phosphoglycerate dehydrogenase
- cow(505103) phosphoglycerate dehydrogenase
- domestic guinea pig(100726801) phosphoglycerate dehydrogenase
- sheep(101111328) phosphoglycerate dehydrogenase
- naked mole-rat(101712402) phosphoglycerate dehydrogenase
- chicken(424381) phosphoglycerate dehydrogenase
- Zebrafish(321928) phosphoglycerate dehydrogenase
- domestic cat(101088505) phosphoglycerate dehydrogenase
- Horse(100059940) phosphoglycerate dehydrogenase
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Antibodies
Anti-3-PGDH Antibody, clone TK-08 13A8, clone TK-08 13A8, from mouse,
human
immunohistochemistry
western blot
western blot
Anti-3-PGDH Antibody, from rabbit, purified by affinity chromatography,
chimpanzee, human, mouse, porcine
immunohistochemistry
western blot
western blot