PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
Sinónimos:
CD140A, PDGFR-2, PDGFR2, RHEPDGFRA
Especie:
Human PDGFRA (5156), Mouse Pdgfra (18595), Rat Pdgfra (25267), chicken PDGFRA (395509), domestic guinea pig Pdgfra (100726209), cow PDGFRA (282301), Zebrafish pdgfra (386856), domestic cat PDGFRA (101090765), sheep PDGFRA (101106012), dog PDGFRA (442860) ...Más
ID UniProtKB:
ID del gen:
- Human(5156) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
- Mouse(18595) platelet derived growth factor receptor, alpha polypeptide
- Rat(25267) platelet derived growth factor receptor, alpha polypeptide
- chicken(395509) platelet-derived growth factor receptor, alpha polypeptide
- domestic guinea pig(100726209) platelet-derived growth factor receptor, alpha polypeptide
- cow(282301) platelet-derived growth factor receptor, alpha polypeptide
- Zebrafish(386856) platelet derived growth factor receptor alpha
- domestic cat(101090765) platelet-derived growth factor receptor, alpha polypeptide
- sheep(101106012) platelet-derived growth factor receptor, alpha polypeptide
- dog(442860) platelet-derived growth factor receptor, alpha polypeptide
- Horse(100059815) platelet-derived growth factor receptor, alpha polypeptide
- naked mole-rat(101697360) platelet-derived growth factor receptor, alpha polypeptide
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CD140a Antibody, clone APA5, clone APA5, Chemicon®, from rat,
Reactividad de especies
mouse
Aplicación
ELISA
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-phospho-PDGFRα (Tyr754) Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-PDGFRα Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
immunoprecipitation (IP)
western blot
western blot
Anti-phospho-PDGFRα (Tyr742) Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
western blot
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
Platelet-Derived Growth Factor-AA human, PDGF-AA, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Especie
human
PDGFRα Protein, active, 50 µg, Active, recombinant human PDGFRα, residues 550-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
Especie
human
PDGFRα (550-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
PDGFR-α, active, GST tagged from mouse, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
mouse
PDGFR-α (T674I), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human