PDGFB
platelet-derived growth factor beta polypeptide
Sinónimos:
PDGF-2, PDGF2, SIS, SSV, c-sis
Especie:
Human PDGFB (5155), Mouse Pdgfb (18591), Rat Pdgfb (24628), naked mole-rat Pdgfb (101698830), dog PDGFB (442986), sheep PDGFB (443545), domestic guinea pig Pdgfb (100731469), cow PDGFB (540106), chicken PDGFB (374128), Zebrafish pdgfb (565324)
ID UniProtKB:
ID del gen:
- Human(5155) Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013]
- Mouse(18591) platelet derived growth factor, B polypeptide
- Rat(24628) platelet-derived growth factor beta polypeptide
- naked mole-rat(101698830) platelet-derived growth factor beta polypeptide
- dog(442986) platelet-derived growth factor beta polypeptide
- sheep(443545) platelet-derived growth factor beta polypeptide
- domestic guinea pig(100731469) platelet-derived growth factor beta polypeptide
- cow(540106) platelet-derived growth factor beta polypeptide
- chicken(374128) platelet-derived growth factor beta polypeptide
- Zebrafish(565324) platelet derived growth factor, B polypeptide
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PDGF-BB Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
ELISA
neutralization
western blot
neutralization
western blot
Anti-PDGF-BB Antibody, clone 6A9.9.11, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Proteins
Referencia del producto
Descripción
Especie
Platelet-Derived Growth Factor-BB human, PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Especie
human
Platelet-Derived Growth Factor from porcine platelets, PDGF, lyophilized powder, suitable for cell culture,
Especie
PDGF-BB recombinante humano, The Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle & connective tissue.,
Especie
human
PDGF-BB human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Especie
human
Platelet-Derived Growth Factor-BB human, PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Especie
human
esiRNA
Referencia del producto
Descripción
Especie