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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

Sinónimos:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Especie:
ID UniProtKB:
ID del gen:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Especie
human
Vinpocetine, ≥98%, solid,
Especie
human
Dipyridamole, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Dipyridamole impurity standard, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Dipyridamole, British Pharmacopoeia (BP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PDE1A,
Especie
human
MISSION® esiRNA, targeting mouse Pde1a,
Especie
mouse