PARP1
poly (ADP-ribose) polymerase 1
Sinónimos:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Especie:
Human PARP1 (142), Mouse Parp1 (11545), Rat Parp1 (25591), Thale Cress PARP1 (817690), chicken PARP1 (396199), Zebrafish parp1 (560788), sheep PARP1 (100135697), domestic cat PARP1 (101081434), Horse PARP1 (100058523), dog PARP1 (490385) ...Más
ID UniProtKB:
ID del gen:
- Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
- Mouse(11545) poly (ADP-ribose) polymerase family, member 1
- Rat(25591) poly (ADP-ribose) polymerase 1
- Thale Cress(817690) poly [ADP-ribose] polymerase 2
- chicken(396199) poly (ADP-ribose) polymerase 1
- Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
- sheep(100135697) poly (ADP-ribose) polymerase 1
- domestic cat(101081434) poly (ADP-ribose) polymerase 1
- Horse(100058523) poly (ADP-ribose) polymerase 1
- dog(490385) poly (ADP-ribose) polymerase 1
- domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
- naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
- cow(286764) poly (ADP-ribose) polymerase 1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Poly ADP-ribose Antibody, clone 10H, clone 10H, from mouse,
Reactividad de especies
human
Aplicación
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti- PARP1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti- Cleaved PARP1 p25 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-phospho-rat PARP1(S373) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
rat
Aplicación
dot blot
Anti-PARP Poly ADP-ribose Polymerase-1 Antibody, serum, Chemicon®,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
ELISA
western blot
western blot
Small Molecule - Inhibitor
Referencia del producto
Descripción
Especie
Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture,
Especie
human
Proteins
Referencia del producto
Descripción
Especie