PARL
presenilin associated, rhomboid-like
Sinónimos:
PSARL, PSARL1, PSENIP2, RHBDS1
Especie:
Human PARL (55486), Mouse Parl (381038), Rat Parl (287979), domestic guinea pig Parl (100722572), naked mole-rat Parl (101719514), chicken PARL (424767), dog PARL (488100), cow PARL (514191), sheep PARL (101102026), Domestic Rabbit PARL (100351338) ...Más
ID UniProtKB:
ID del gen:
- Human(55486) Summary: This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(381038) presenilin associated, rhomboid-like
- Rat(287979) presenilin associated, rhomboid-like
- domestic guinea pig(100722572) presenilin associated, rhomboid-like
- naked mole-rat(101719514) presenilin associated, rhomboid-like
- chicken(424767) presenilin associated, rhomboid-like
- dog(488100) presenilin associated, rhomboid-like
- cow(514191) presenilin associated, rhomboid-like
- sheep(101102026) presenilin associated, rhomboid-like
- Domestic Rabbit(100351338) presenilin associated, rhomboid-like
- domestic cat(101091042) presenilin associated, rhomboid-like
- Horse(100058851) presenilin associated, rhomboid-like
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