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Merck

NFKBIA

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Sinónimos:
IKBA, MAD-3, NFKBI
Especie:
ID UniProtKB:
ID del gen:
  • Human(4792) Summary: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
  • Mouse(18035) nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • Rat(25493) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • naked mole-rat(101709256) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic guinea pig(100723189) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic cat(101090622) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • sheep(780520) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • chicken(396093) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • dog(480291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • cow(282291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Phospho-IκBα-Ser32/36 Antibody, clone 1I11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-p-IκBα-Ser32 Antibody, clone 11D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, porcine
Aplicación
affinity binding assay
flow cytometry

immunocytochemistry

inhibition assay

western blot
Anti- IκBα antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-IκBα Antibody, serum, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Phospho-IκBα-S32 antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human NFKBIA,
Especie
human
MISSION® esiRNA, targeting mouse Nfkbia,
Especie
mouse