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Merck

MMP9

matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

Sinónimos:
CLG4B, GELB, MANDP2, MMP-9
Especie:
ID UniProtKB:
ID del gen:
  • Human(4318) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
  • Mouse(17395) matrix metallopeptidase 9
  • Rat(81687) matrix metallopeptidase 9
  • Domestic Rabbit(100008993) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • sheep(100192422) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • dog(403885) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • domestic cat(101084185) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • cow(282871) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • domestic guinea pig(100728510) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • chicken(395387) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • Horse(100169862) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • naked mole-rat(101717243) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • Zebrafish(406397) matrix metalloproteinase 9
  • Horse(100056599) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-MMP-9, dominio catalítico, Chemicon®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MMP-9 (Ab-1) Mouse mAb (6-6B), lyophilized, clone 6-6B, Calbiochem®,
Reactividad de especies
human
Aplicación
Anti-MMP-9 Antibody, clone 9D4.2, clone 9D4.2, Chemicon®, from mouse,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-MMP-9 (Active) Antibody, clone 4A3, clone 4A3, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-MMP-9 (Ab-3) Mouse mAb (56-2A4), liquid, clone 56-2A4, Calbiochem®,
Reactividad de especies
guinea pig, human, rabbit, rat
Aplicación

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
α-Sexithiophene, ,
Especie
human, rat
Marimastat, ≥98% (HPLC),
Especie
human, rat, mouse
CP-101537, ≥98% (HPLC),
Especie
human, rat, mouse
CP-471474, ≥98% (HPLC),
Especie
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Especie
human, rat, mouse

Proteins

Referencia del producto
Descripción
Especie
Matrix Metalloproteinase-9 human, recombinant, >90% (SDS-PAGE), buffered aqueous solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MMP9,
Especie
human
MISSION® esiRNA, targeting mouse Mmp9,
Especie
mouse