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Merck

MMP7

matrix metallopeptidase 7 (matrilysin, uterine)

Sinónimos:
MMP-7, MPSL1, PUMP-1
Especie:
ID UniProtKB:
ID del gen:
  • Human(4316) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17393) matrix metallopeptidase 7
  • Rat(25335) matrix metallopeptidase 7
  • domestic guinea pig(100727130) matrix metallopeptidase 7 (matrilysin, uterine)
  • dog(489432) matrix metallopeptidase 7 (matrilysin, uterine)
  • chicken(418983) matrix metallopeptidase 7 (matrilysin, uterine)
  • naked mole-rat(101718114) matrix metallopeptidase 7 (matrilysin, uterine)
  • cow(286794) matrix metallopeptidase 7 (matrilysin, uterine)
  • sheep(100192317) matrix metallopeptidase 7 (matrilysin, uterine)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-MMP-7 Antibody, clone 2B3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
immunocytochemistry

western blot
Anti-MMP-7 Antibody, clone ID-2, clone ID-2, Chemicon®, from mouse,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-MMP-7 (Ab-1) Mouse mAb (141-7B2), liquid, clone 141-7B2, Calbiochem®,
Reactividad de especies
human
Aplicación
Anti-MMP7 Antibody, clone 9D8S10, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Doxycycline monohydrate, ,
Especie
human
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Marimastat, ≥98% (HPLC),
Especie
human, rat, mouse
CP-101537, ≥98% (HPLC),
Especie
human, rat, mouse
CP-471474, ≥98% (HPLC),
Especie
human, rat, mouse

Proteins

Referencia del producto
Descripción
Especie
Matrix Metalloproteinase-7 human, ~0.1 mg/mL, recombinant, expressed in E. coli, buffered aqueous solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MMP7,
Especie
human