ME2
malic enzyme 2, NAD(+)-dependent, mitochondrial
Sinónimos:
ODS1
Especie:
Human ME2 (4200), Mouse Me2 (107029), Rat Me2 (307270), Zebrafish me2 (445233), dog ME2 (476198), domestic cat ME2 (101092963), Horse ME2 (100069637), cow ME2 (507817), sheep ME2 (101117980), domestic guinea pig Me2 (100720540)
ID UniProtKB:
ID del gen:
- Human(4200) Summary: This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009]
- Mouse(107029) malic enzyme 2, NAD(+)-dependent, mitochondrial
- Rat(307270) malic enzyme 2, NAD(+)-dependent, mitochondrial
- Zebrafish(445233) malic enzyme 2, NAD(+)-dependent, mitochondrial
- dog(476198) malic enzyme 2, NAD(+)-dependent, mitochondrial
- domestic cat(101092963) malic enzyme 2, NAD(+)-dependent, mitochondrial
- Horse(100069637) malic enzyme 2, NAD(+)-dependent, mitochondrial
- cow(507817) malic enzyme 2, NAD(+)-dependent, mitochondrial
- sheep(101117980) malic enzyme 2, NAD(+)-dependent, mitochondrial
- domestic guinea pig(100720540) malic enzyme 2, NAD(+)-dependent, mitochondrial
- naked mole-rat(101702791) malic enzyme 2, NAD(+)-dependent, mitochondrial
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