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Merck

MAPT

microtubule-associated protein tau

Sinónimos:
DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU
Especie:
ID UniProtKB:
ID del gen:
  • Human(4137) Summary: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
  • Mouse(17762) microtubule-associated protein tau
  • Rat(29477) microtubule-associated protein tau
  • domestic guinea pig(100735442) microtubule-associated protein tau
  • chicken(426737) microtubule-associated protein tau
  • sheep(101121024) microtubule-associated protein tau
  • Domestic Rabbit(100344003) microtubule-associated protein tau
  • cow(281296) microtubule-associated protein tau
  • Goat(100860820) microtubule-associated protein tau
  • domestic cat(101089557) microtubule-associated protein tau
  • Horse(100054638) microtubule-associated protein tau
  • dog(480488) microtubule-associated protein tau
  • naked mole-rat(101719489) microtubule-associated protein tau

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-Tau (isoforma de 3 repeticiones RD3), clon 8E6/C11, culture supernatant, clone 8E6/C11, Upstate®,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anticuerpo oligómero anti-Tau (T22), serum, from rabbit,
Reactividad de especies
human
Aplicación
ELISA
dot blot

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

neutralization

western blot
Anti-Tau Antibody, clone Tau 12 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-Phospho-Tau-T217 antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
western blot
Anti-Phospho-Tau-S396 antibody produced in rabbit, ,
Reactividad de especies
human, rat
Aplicación
western blot

Proteins

Referencia del producto
Descripción
Especie
Tau-441 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), lyophilized powder,
Especie
human
Tau Protein Ladder, 6 isoforms, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
TAU-441, GSK3BETA-Phosphorylated, recombinant,
Especie
human
Tau-441 human, recombinant, lyophilized powder, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Especie
human
TAU-441, TTBK1-Phosphorylated, recombinant,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MAPT,
Especie
human