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Merck

LRBA

LPS-responsive vesicle trafficking, beach and anchor containing

Sinónimos:
BGL, CDC4L, CVID8, LAB300, LBA
Especie:
ID UniProtKB:
ID del gen:
  • Human(987) Summary: The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
  • Mouse(80877) LPS-responsive beige-like anchor
  • Rat(361975) LPS-responsive vesicle trafficking, beach and anchor containing
  • Zebrafish(100317557) LPS-responsive vesicle trafficking, beach and anchor containing
  • chicken(422476) LPS-responsive vesicle trafficking, beach and anchor containing
  • dog(475463) LPS-responsive vesicle trafficking, beach and anchor containing
  • domestic cat(101093432) LPS-responsive vesicle trafficking, beach and anchor containing
  • domestic guinea pig(100721090) LPS-responsive vesicle trafficking, beach and anchor containing
  • cow(524279) LPS-responsive vesicle trafficking, beach and anchor containing
  • sheep(101106365) LPS-responsive vesicle trafficking, beach and anchor containing
  • naked mole-rat(101711663) LPS-responsive vesicle trafficking, beach and anchor containing
  • Horse(100062459) LPS-responsive vesicle trafficking, beach and anchor containing

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-LRBA Antibody, clone 2D4.1, clone 2D4.1, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-LRBA Antibody, clone 3H22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse
Aplicación
flow cytometry
immunocytochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human LRBA,
Especie
human