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Merck

KRAS

Kirsten rat sarcoma viral oncogene homolog

Sinónimos:
C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Especie:
ID UniProtKB:
ID del gen:
  • Human(3845) Summary: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
  • Mouse(16653) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • Rat(24525) Kirsten rat sarcoma viral oncogene
  • Zebrafish(445289) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • sheep(101114005) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • naked mole-rat(101718997) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • chicken(418207) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • dog(403871) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • cow(541140) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • domestic guinea pig(100716262) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Kras Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-Pan-Ras (Ab-3) Mouse mAb (RAS 10), liquid, clone RAS 10, Calbiochem®,
Reactividad de especies
human, mouse, rat
Aplicación
Anti-Pan-Ras Antibody, clone RAS 10, clone RAS 10, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
western blot
Anti-c-K-Ras Antibody, clone 234-4.2, clone 234-4.2, from mouse,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot
Anti-Phospho-KRAS-S89 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

Proteins

Referencia del producto
Descripción
Especie
KRAS (Mature Form), Active, PRECISIO® Kinase, recombinant,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse KRAS,
Especie
mouse
MISSION® esiRNA, targeting human KRAS,
Especie
human