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Merck

KLK3

kallikrein-related peptidase 3

Sinónimos:
APS, KLK2A1, PSA, hK3
Especie:
Human KLK3 (354)
ID UniProtKB:
P07288, C9JXH3, G3V0H4, G3XAE3, Q15096, Q16272, Q86TG8, Q8IXI4
ID del gen:
  • Human(354) Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
ZRB1972
Anti-PSA Antibody, clone 1E10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
324R-1
PSA (EP109) Rabbit Monoclonal Primary Antibody, ,
Reactividad de especies
Aplicación
immunohistochemistry
AMAB91567
Monoclonal Anti-KLK3 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9414, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
SAB4702007
Monoclonal Anti-PSA Biotin produced in mouse, ,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
western blot
MABX5523
Anti-PSA (10mg) KC, from mouse,
Reactividad de especies
human
Aplicación
ELISA
immunodiffusion

Proteins

Número de producto
Descripción
Especie
SRP6058
Kallikrein-3 human, recombinant, expressed in human cells, ≥95% (SDS-PAGE),
Especie
human

esiRNA

Número de producto
Descripción
Especie
EHU156951
MISSION® esiRNA, targeting human KLK3,
Especie
human