KLHL3
kelch-like family member 3
Sinónimos:
PHA2D
Especie:
Human KLHL3 (26249), Mouse Klhl3 (100503085), Rat Klhl3 (498697), domestic guinea pig Klhl3 (100732587), naked mole-rat Klhl3 (101699865), sheep KLHL3 (101107091), Horse KLHL3 (100062564), cow KLHL3 (533364), Domestic Rabbit KLHL3 (100343290), domestic cat KLHL3 (101083647) ...Más
ID UniProtKB:
ID del gen:
- Human(26249) Summary: This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]
- Mouse(100503085) kelch-like 3
- Rat(498697) kelch-like family member 3
- domestic guinea pig(100732587) kelch-like family member 3
- naked mole-rat(101699865) kelch-like family member 3
- sheep(101107091) kelch-like 3 (Drosophila)
- Horse(100062564) kelch-like 3 (Drosophila)
- cow(533364) kelch-like family member 3
- Domestic Rabbit(100343290) kelch-like 3 (Drosophila)
- domestic cat(101083647) kelch-like 3 (Drosophila)
- Zebrafish(568556) kelch-like 3 (Drosophila)
- chicken(416303) kelch-like 3 (Drosophila)
- dog(481523) kelch-like 3 (Drosophila)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
esiRNA
Número de producto
Descripción
Especie