ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Sinónimos:
CD11A, LFA-1, LFA1A
Especie:
Human ITGAL (3683), Mouse Itgal (16408), Rat Itgal (308995), domestic cat ITGAL (101085940), dog ITGAL (489905), Horse ITGAL (100065508), sheep ITGAL (641296), cow ITGAL (281874), Domestic Rabbit ITGAL (100356927), domestic guinea pig Itgal (100713143)
ID UniProtKB:
ID del gen:
- Human(3683) Summary: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(16408) integrin alpha L
- Rat(308995) integrin, alpha L
- domestic cat(101085940) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- dog(489905) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- Horse(100065508) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- sheep(641296) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- cow(281874) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- Domestic Rabbit(100356927) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- domestic guinea pig(100713143) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- naked mole-rat(101723643) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CD11a Antibody, clone BU17, clone BU17, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
Anti-CD11a/LFA-1A/ITGAL antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Anti-CD11a Antibody, clone TS2/4, ,
Reactividad de especies
human
Aplicación
affinity chromatography
electrophoresis
flow cytometry
immunofluorescence
immunoprecipitation (IP)
inhibition assay
radioimmunoassay
electrophoresis
flow cytometry
immunofluorescence
immunoprecipitation (IP)
inhibition assay
radioimmunoassay
Anti-CD11a Antibody, clone 2J15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot