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Merck

IRAK3

interleukin-1 receptor-associated kinase 3

Sinónimos:
ASRT5, IRAKM
Especie:
ID UniProtKB:
ID del gen:
  • Human(11213) Summary: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
  • Mouse(73914) interleukin-1 receptor-associated kinase 3
  • Rat(314870) interleukin-1 receptor-associated kinase 3
  • Zebrafish(567444) interleukin-1 receptor-associated kinase 3
  • dog(481150) interleukin-1 receptor-associated kinase 3
  • domestic cat(101093197) interleukin-1 receptor-associated kinase 3
  • cow(510342) interleukin-1 receptor-associated kinase 3
  • naked mole-rat(101704873) interleukin-1 receptor-associated kinase 3
  • sheep(101115273) interleukin-1 receptor-associated kinase 3
  • domestic guinea pig(100729478) interleukin-1 receptor-associated kinase 3

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
KD-Validated Anti IRAK3 Antibody, clone 23GB875, Rabbit Monoclonal, clone 23GB875, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence

western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human IRAK3,
Especie
human
MISSION® esiRNA, targeting mouse Irak3,
Especie
mouse