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Merck

IL12A

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

Sinónimos:
CLMF, IL-12A, NFSK, NKSF1, P35
Especie:
ID UniProtKB:
ID del gen:
  • Human(3592) Summary: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
  • Mouse(16159) interleukin 12a
  • Rat(84405) interleukin 12A
  • domestic guinea pig(100379543) interleukin 12a
  • chicken(407090) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Zebrafish(445410) interleukin 12a
  • Horse(100034215) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • domestic cat(493741) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • dog(403977) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • cow(281856) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Goat(100861293) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • sheep(443064) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • naked mole-rat(101701392) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-IL-12A Antibody, clone 1G10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
baboon, bovine, canine, feline, goat, human, monkey, mouse, porcine, sheep
Aplicación
affinity binding assay
flow cytometry

western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human IL12A,
Especie
human
MISSION® esiRNA, targeting mouse Il12a,
Especie
mouse