HUWE1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
Sinónimos:
ARF-BP1, HECTH9, HSPC272, Ib772, LASU1, MULE, URE-B1, UREB1
Especie:
Human HUWE1 (10075), Mouse Huwe1 (59026), Rat Huwe1 (501546), Zebrafish huwe1 (559439), naked mole-rat Huwe1 (101713610), domestic guinea pig Huwe1 (100722589), sheep HUWE1 (101119368), cow HUWE1 (511826), Horse HUWE1 (100060375), domestic cat HUWE1 (101091091)
ID UniProtKB:
ID del gen:
- Human(10075) Summary: This gene encodes a member of the HECT E3 ubiquitin ligase family. The HECT domain lies in the C-terminus and contains the active-site cysteine which forms an intermediate ubiquitin-thioester bond. E3 family members are divided into three subfamilies based on their protein-protein interaction domains; this gene encodes a member of the SI(ngle)-HECT E3 subfamily. In lung, breast, and colorectal carcinomas, this gene is highly expressed. Mutations in this gene has been found in 3 unrelated families with X-linked syndromic mental retardation, Turner type. [provided by RefSeq, Nov 2009]
- Mouse(59026) HECT, UBA and WWE domain containing 1
- Rat(501546) HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
- Zebrafish(559439) HECT, UBA and WWE domain containing 1
- naked mole-rat(101713610) HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
- domestic guinea pig(100722589) HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
- sheep(101119368) HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
- cow(511826) HECT, UBA and WWE domain containing 1
- Horse(100060375) HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
- domestic cat(101091091) HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
- dog(480931) HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
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