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Merck

HTR2B

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

Sinónimos:
5-HT(2B), 5-HT2B
Especie:
ID UniProtKB:
ID del gen:
  • Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
  • Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
  • Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
  • Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
BW 723C86, ≥98% (HPLC),
Especie
human
Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Quipazine maleate salt, ,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Ketanserin (+)-tartrate salt, ≥97%, solid,
Especie
human
Cyclobenzaprine hydrochloride, ,
Especie
human
Cyproheptadine hydrochloride sesquihydrate, ≥98% (TLC), solid,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-Htr2B Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14576, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
western blot
Anti-HTR2B (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, guinea pig, horse, human, mouse, pig
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Mifepristone, ≥98%,
Especie
human, mouse, rat

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
Mifepristone, ≥98%,
Especie
human, mouse, rat

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
5-Hydroxy-L-tryptophan, powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human HTR2B,
Especie
human