HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
Sinónimos:
11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1
Especie:
Human HSD11B1 (3290), Mouse Hsd11b1 (15483), Rat Hsd11b1 (25116), domestic cat HSD11B1 (100529248), dog HSD11B1 (449023), domestic guinea pig Hsd11b1 (100135542), cow HSD11B1 (282589), sheep HSD11B1 (443409), naked mole-rat Hsd11b1 (101716800), chicken HSD11B1 (419861)
ID UniProtKB:
ID del gen:
- Human(3290) Summary: The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011]
- Mouse(15483) hydroxysteroid 11-beta dehydrogenase 1
- Rat(25116) hydroxysteroid 11-beta dehydrogenase 1
- domestic cat(100529248) hydroxysteroid (11-beta) dehydrogenase 1
- dog(449023) hydroxysteroid (11-beta) dehydrogenase 1
- domestic guinea pig(100135542) hydroxysteroid 11-beta dehydrogenase 1
- cow(282589) hydroxysteroid (11-beta) dehydrogenase 1
- sheep(443409) hydroxysteroid (11-beta) dehydrogenase 1
- naked mole-rat(101716800) hydroxysteroid (11-beta) dehydrogenase 1
- chicken(419861) hydroxysteroid (11-beta) dehydrogenase 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Inhibitor
Referencia del producto
Descripción
Especie
esiRNA
Referencia del producto
Descripción
Especie