HDAC8
histone deacetylase 8
Sinónimos:
CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS
Especie:
Human HDAC8 (55869), Mouse Hdac8 (70315), Rat Hdac8 (363481), domestic guinea pig Hdac8 (100721893), chicken HDAC8 (422182), Zebrafish hdac8 (406740), domestic cat HDAC8 (101096383), dog HDAC8 (480957), sheep HDAC8 (101110121), cow HDAC8 (540666)
ID UniProtKB:
ID del gen:
- Human(55869) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(70315) histone deacetylase 8
- Rat(363481) histone deacetylase 8
- domestic guinea pig(100721893) histone deacetylase 8
- chicken(422182) histone deacetylase 8
- Zebrafish(406740) histone deacetylase 8
- domestic cat(101096383) histone deacetylase 8
- dog(480957) histone deacetylase 8
- sheep(101110121) histone deacetylase 8
- cow(540666) histone deacetylase 8
- naked mole-rat(101697998) histone deacetylase 8
Custom & Knockdown Gene Products
siRNA
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shRNA
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-HDAC8 Antibody, serum, Upstate®,
Reactividad de especies
human, mouse
Aplicación
immunoprecipitation (IP)
western blot
western blot
[KO Validated]Anti-HDAC8 Antibody, clone 1O2Y5, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Kits
Referencia del producto
Descripción
Especie
Histone Deacetylase 8 (HDAC8) Inhibitor Screening Kit, 100 assays in 96 well plates,
Especie
human, mouse