Saltar al contenido
Merck

HDAC3

histone deacetylase 3

Sinónimos:
HD3, RPD3, RPD3-2
Especie:
ID UniProtKB:
ID del gen:
  • Human(8841) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
  • Mouse(15183) histone deacetylase 3
  • Rat(84578) histone deacetylase 3
  • fruit fly(44446) Histone deacetylase 3
  • Zebrafish(393965) histone deacetylase 3
  • cow(404125) histone deacetylase 3
  • chicken(395506) histone deacetylase 3
  • sheep(101107092) histone deacetylase 3
  • domestic guinea pig(100718985) histone deacetylase 3
  • dog(478040) histone deacetylase 3
  • domestic cat(101100941) histone deacetylase 3
  • naked mole-rat(101708680) histone deacetylase 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-HDAC3 Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-HDAC3 Antibody, clone 1M1O7, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunoprecipitation (IP)
western blot
Anti-HDAC3 Antibody, clone 1H19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-HDAC3 Antibody, clone 3G6, clone 3G6, Upstate®, from mouse,
Reactividad de especies
bovine, hamster, human, mouse
Aplicación
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-HDAC3 Rabbit Monoclonal Antibody, clone RM439, affinity purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
SAHA, ≥98% (HPLC),
Especie
human
Romidepsin, ≥98% (HPLC),
Especie
human
CI−994, ≥98% (HPLC), powder,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
HDAC3 human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human HDAC3,
Especie
human
MISSION® esiRNA, targeting mouse Hdac3,
Especie
mouse