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Merck

GPC3

glypican 3

Sinónimos:
DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
Especie:
Human GPC3 (2719), Mouse Gpc3 (14734), Rat Gpc3 (25236), Zebrafish gpc3 (387365), domestic guinea pig Gpc3 (100726246), chicken GPC3 (770863), Domestic Rabbit GPC3 (100351858), sheep GPC3 (101119285), cow GPC3 (615239), domestic cat GPC3 (101094739)
ID UniProtKB:
P51654, C9JLE3, G3V1R0, Q2L880, Q2L882
ID del gen:
  • Human(2719) Summary: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
  • Mouse(14734) glypican 3
  • Rat(25236) glypican 3
  • Zebrafish(387365) glypican 3
  • domestic guinea pig(100726246) glypican 3
  • chicken(770863) glypican 3
  • Domestic Rabbit(100351858) glypican 3
  • sheep(101119285) glypican 3
  • cow(615239) glypican 3
  • domestic cat(101094739) glypican 3
  • dog(481056) glypican 3

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
MABC667
Anti-GPC3 Antibody, clone 9C2, ascites fluid, clone 9C2, from mouse,
Reactividad de especies
human, mouse
Aplicación
flow cytometry
immunofluorescence
immunohistochemistry
western blot
AMAB91803
Anti-GPC3 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL12711, purified by using Protein A, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

Proteins

Referencia del producto
Descripción
Especie
G1921
Glypican 3, recombinant, expressed in NSO cells,
Especie
human
SRP0610
Monkey (M. fascicularis) GPC3, His-Tag, recombinant, expressed in HEK 293 cells,
Especie
mouse

esiRNA

Referencia del producto
Descripción
Especie
EMU022581
MISSION® esiRNA, targeting mouse Gpc3,
Especie
mouse
EHU001531
MISSION® esiRNA, targeting human GPC3,
Especie
human