GP1BA
glycoprotein Ib (platelet), alpha polypeptide
Sinónimos:
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
Especie:
Human GP1BA (2811), Mouse Gp1ba (14723), Rat Gp1ba (691992), chicken GP1BA (420059), naked mole-rat Gp1ba (101717127), domestic guinea pig Gp1ba (100717535), sheep GP1BA (101109891), cow GP1BA (504977), domestic cat GP1BA (101092307), dog GP1BA (403638)
ID UniProtKB:
ID del gen:
- Human(2811) Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]
- Mouse(14723) glycoprotein 1b, alpha polypeptide
- Rat(691992) glycoprotein Ib (platelet), alpha polypeptide
- chicken(420059) glycoprotein Ib (platelet), alpha polypeptide
- naked mole-rat(101717127) glycoprotein Ib (platelet), alpha polypeptide
- domestic guinea pig(100717535) glycoprotein Ib (platelet), alpha polypeptide
- sheep(101109891) glycoprotein Ib (platelet), alpha polypeptide
- cow(504977) glycoprotein Ib (platelet), alpha polypeptide
- domestic cat(101092307) glycoprotein Ib (platelet), alpha polypeptide
- dog(403638) glycoprotein Ib (platelet), alpha polypeptide
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Milli-Mark® Anti-CD42b-PE Antibody, clone AN51, clone AN51, Milli-Mark®, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
Anti-CD42b/GP1BA Antibody, clone 1C9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry
western blot
immunocytochemistry
western blot