GLIS2
GLIS family zinc finger 2
Sinónimos:
NKL, NPHP7
Especie:
Human GLIS2 (84662), Mouse Glis2 (83396), Rat Glis2 (302946), Horse GLIS2 (100066071), domestic cat GLIS2 (101095217), dog GLIS2 (490028), naked mole-rat Glis2 (101718299), sheep GLIS2 (101102282), chicken GLIS2 (374023), domestic guinea pig Glis2 (100718347)
ID UniProtKB:
ID del gen:
- Human(84662) Summary: This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010]
- Mouse(83396) GLIS family zinc finger 2
- Rat(302946) GLIS family zinc finger 2
- Horse(100066071) GLIS family zinc finger 2
- domestic cat(101095217) GLIS family zinc finger 2
- dog(490028) GLIS family zinc finger 2
- naked mole-rat(101718299) GLIS family zinc finger 2
- sheep(101102282) GLIS family zinc finger 2
- chicken(374023) GLIS family zinc finger 2
- domestic guinea pig(100718347) GLIS family zinc finger 2
- cow(527935) GLIS family zinc finger 2
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GLIS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
western blot
esiRNA
Referencia del producto
Descripción
Especie