GCK
glucokinase (hexokinase 4)
Sinónimos:
FGQTL3, GK, GLK, HHF3, HK4, HKIV, HXKP, LGLK, MODY2
Especie:
Human GCK (2645), Mouse Gck (103988), Rat Gck (24385), Zebrafish gck (751668), chicken GCK (430370), domestic cat GCK (100037406), dog GCK (606490), sheep GCK (101117412), cow GCK (616576), Horse GCK (100051836) ...Más
ID UniProtKB:
ID del gen:
- Human(2645) Summary: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009]
- Mouse(103988) glucokinase
- Rat(24385) glucokinase
- Zebrafish(751668) glucokinase (hexokinase 4, maturity onset diabetes of the young 2)
- chicken(430370) glucokinase (hexokinase 4)
- domestic cat(100037406) glucokinase (hexokinase 4)
- dog(606490) glucokinase (hexokinase 4)
- sheep(101117412) glucokinase (hexokinase 4)
- cow(616576) glucokinase (hexokinase 4)
- Horse(100051836) glucokinase (hexokinase 4)
- naked mole-rat(101721664) glucokinase (hexokinase 4)
- domestic guinea pig(100717630) glucokinase (hexokinase 4)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Glucokinase/GCK Antibody, clone 9G1.2, clone 9G1.2, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-Glucokinase (GCK) Antibody, clone 4K9D5, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunoprecipitation (IP)
western blot
western blot
esiRNA
Referencia del producto
Descripción
Especie