GAD1
glutamate decarboxylase 1 (brain, 67kDa)
Sinónimos:
CPSQ1, GAD, SCP
Especie:
Human GAD1 (2571), Mouse Gad1 (14415), Rat Gad1 (24379), sheep GAD1 (101117393), domestic cat GAD1 (493699), domestic guinea pig Gad1 (100271904), naked mole-rat Gad1 (101725846), cow GAD1 (517552), fruit fly Gad1 (38484), chicken GAD1 (395743)
ID UniProtKB:
ID del gen:
- Human(2571) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
- Mouse(14415) glutamate decarboxylase 1
- Rat(24379) glutamate decarboxylase 1
- sheep(101117393) glutamate decarboxylase 1 (brain, 67kDa)
- domestic cat(493699) glutamate decarboxylase 1 (brain, 67kDa)
- domestic guinea pig(100271904) glutamate decarboxylase 1
- naked mole-rat(101725846) glutamate decarboxylase 1 (brain, 67kDa)
- cow(517552) glutamate decarboxylase 1 (brain, 67kDa)
- fruit fly(38484) Glutamic acid decarboxylase 1
- chicken(395743) glutamate decarboxylase 1 (brain, 67kDa)
- dog(478794) glutamate decarboxylase 1 (brain, 67kDa)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-GAD67, clon 1G10.2, clone 1G10.2, Chemicon®, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-GAD67 Antibody, clone 1G10.2, Biotin Conjugate, clone 1G10.2, from mouse, biotin conjugate,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry
immunohistochemistry
Anti-GAD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-GAD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-GAD67/GAD1 Antibody, clone 4I8S8, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot